Prevalence of microalbuminuria in Type-2 diabetes mellitus (DM) (negative by strip test)

Prevalence of microalbuminuria in Type-2 diabetes mellitus (DM) (negative by strip test)

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Diabetic Nephropathy and end-stage renal failure are still a major cause of mortality amongst patients with diabetes mellitus.Microalbuminuria has been shown to be a strong predictor of progressive renal disorders and a potent risk marker for cardiovascular disease.However the prevalence of microalbuminuria in DM type 2 patients in Thai people is less certain.Thus, we examined the prevalence of microalbuminuria in DM.

patients in Lampang Hospital study.Two hundred seventy patients with DM type 2 attending to outpatient medical unit were randomly trikes selected.In a first interview, a strip test for protein was performed on a singe-spot morning urine sample (no hematuria).The patient was excluded if proteinuria was present; if proteinuria was absent an microalbuminuria and creatinine were performed by automated chemistry analyzer.

Urine helmets albumin-to-creatinine ratio was calculated.Blood sample was obtained to determine glucose and HbA1C.Prevalence of microalbuminuria (MA) was 24.8%, normal function (NF) was found in 66.

2% and overt nephropathy (ON) in 9%, Fasting Blood glucose and HbA1C were poorly controlled in all groups.Conclusion: Microalbuminuria; the presence of low but abnormal levels of albumin in the urine is the earliest sign of nephropathy and specific to diabetic nephropathy.Bull Chiang Mai Assoc Med Sci 2008; 41: 103-110.